I aim to use targeted delivery nanoparticles to alter cancer tissue. Others have used particles to alter tissue back to its original state. I wanted to question terminal organs and possible routes to alter. Terminal organs are like the heart, brain, and lungs. The normal metasis is from particles travelling from the lungs to the brain. From initial research particle breaking from initial tumours are like nerves attached to small cancer cells. Others stated retroviruses can invade existing cells and cause them to mutate to cancer particles. As an example, others said heavy smoking might lead to lung cancer.